No Second Chances is the third cinematic in the main story of Hitman. The previous cinematic is He Could be Dangerous and the next cinematic is Call Me 47.

In the storyline, No Second Chances follows the prologue Freeform Training and is followed by the prologue The Final Test.

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Story 1. A Blank Slate - 2. He Could be Dangerous - 3. No Second Chances - 4. Call Me 47 - 5. The Secrets of the Global Elite - 6. The Key