Keycard Reader is an interactable object available in Hitman. It can be found in the World of Tomorrow episodic mission.

Keycard readers can be found outside certain locked doors. These doors can not be opened with a key and they can not be accessed through at all, even if you have a lockpick or a crowbar.

Keycard readers in Sapienza are mainly connected to doors leading into parts of the Villa Caruso mansion in which case a Mansion Keycard is needed, and also to doors leading into parts of the Ether field lab underground in which case a Biolab Keycard is needed instead.

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